5-(4-CHLOROPHENYL)-4-METHYL-3-(1-(2-PHENYLETHYL)PIPERIDIN-4-YL)ISOXAZOLE HYDROCHLORIDE
5-(4-CHLOROPHENYL)-4-METHYL-3-(1-(2-PHENYLETHYL)PIPERIDIN-4-YL)ISOXAZOLE HYDROCHLORIDE Basic information
- Product Name:
- 5-(4-CHLOROPHENYL)-4-METHYL-3-(1-(2-PHENYLETHYL)PIPERIDIN-4-YL)ISOXAZOLE HYDROCHLORIDE
- Synonyms:
-
- 5-(4-CHLOROPHENYL)-4-METHYL-3-(1-(2-PHENYLETHYL)PIPERIDIN-4-YL)ISOXAZOLE HYDROCHLORIDE
- L-741,742 HYDROCHLORIDE
- L-741,742HCl
- L 741742
- Piperidine, 4-[5-(4-chlorophenyl)-4-methyl-3-isoxazolyl]-1-(2-phenylethyl)-
- 742
- L 741742 (free base)
- CAS:
- 156337-32-5
- MF:
- C23H25ClN2O
- MW:
- 380.91
- Mol File:
- 156337-32-5.mol
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5-(4-CHLOROPHENYL)-4-METHYL-3-(1-(2-PHENYLETHYL)PIPERIDIN-4-YL)ISOXAZOLE HYDROCHLORIDE Chemical Properties
- storage temp.
- Store at RT
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5-(4-CHLOROPHENYL)-4-METHYL-3-(1-(2-PHENYLETHYL)PIPERIDIN-4-YL)ISOXAZOLE HYDROCHLORIDE Usage And Synthesis
Uses
L-741,742 Hydrochloride is a D4 dopamine receptor antagonist used in the treatment of psychological diseases such as depression, schizophrenia. Antipsychotic.
Definition
ChEBI: 5-(4-chlorophenyl)-4-methyl-3-[1-(2-phenylethyl)-4-piperidinyl]isoxazole is a primary amine.
Biological Activity
A potent and highly selective D 4 dopamine receptor antagonist, with K i values of > 1700, 770 and 3.5 nM at cloned human D 2 , D 3 and D 4 receptors.
5-(4-CHLOROPHENYL)-4-METHYL-3-(1-(2-PHENYLETHYL)PIPERIDIN-4-YL)ISOXAZOLE HYDROCHLORIDESupplier
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