C2 Adamantanyl Galactosylceramide (d18:1/2:0)
C2 Adamantanyl Galactosylceramide (d18:1/2:0) Basic information
- Product Name:
- C2 Adamantanyl Galactosylceramide (d18:1/2:0)
- Synonyms:
-
- C2 Adamantanyl Galactosylceramide (d18:1/2:0)
- Tricyclo[3.3.1.13,7]decane-1-acetamide, N-[(1S,2R,3E)-1-[(β-D-galactopyranosyloxy)methyl]-2-hydroxy-3-heptadecen-1-yl]-
- Adamantanyl Galactosyl(β) Ceramide
- CAS:
- 574738-16-2
- MF:
- C36H63NO8
- MW:
- 637.9
- Mol File:
- 574738-16-2.mol
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C2 Adamantanyl Galactosylceramide (d18:1/2:0) Chemical Properties
- Boiling point:
- 830.6±65.0 °C(Predicted)
- Density
- 1.17±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 12.92±0.70(Predicted)
- form
- powder
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C2 Adamantanyl Galactosylceramide (d18:1/2:0) Usage And Synthesis
Biological Activity
Adamantyl galactosylceramide (adaGalCer), a glycosphingolipid (GSL) analog, modulates abnormal GSL turnover. It functions as an inhibitor and an alternative substrate to regulate cellular GSL metabolism in a particular manner. AdaGalCer blocks cell sulfatide synthesis and microsomal globotriaosyl ceramide (Gb3) synthesis. It reduces glucosylceramide (GlcCer) levels in normal and lysosomal storage disease (LSD) cells.