17(R)-Resolvin D4
17(R)-Resolvin D4 Basic information
- Product Name:
- 17(R)-Resolvin D4
- Synonyms:
-
- 17(R)-Resolvin D4
- 6,8,10,13,15,19-Docosahexaenoic acid, 4,5,17-trihydroxy-, (4S,5R,6E,8E,10Z,13Z,15E,17R,19Z)-
- CAS:
- 528583-89-3
- MF:
- C22H32O5
- MW:
- 376.49
- Mol File:
- 528583-89-3.mol
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17(R)-Resolvin D4 Chemical Properties
- Boiling point:
- 609.2±55.0 °C(Predicted)
- Density
- 1.101±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 50 mg/ml; DMSO: unstable; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.5 mg/ml
- pka
- 4.50±0.10(Predicted)
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17(R)-Resolvin D4 Usage And Synthesis
Description
17(R)-Resolvin D4 (17(R)-RvD4) is an aspirin-triggered epimer of RvD4 .1
Definition
ChEBI: Aspirin-triggered resolvin D4 is a member of the class of resolvins that is (6E,8E,10Z,13Z,15E,19Z)-docosahexaenoic acid carrying three hydroxy substituents at positions 4, 5 and 17 (the 4S,5R,17R-stereoisomer). It has a role as an anti-inflammatory agent, a human xenobiotic metabolite and a mouse metabolite. It is a resolvin, a secondary allylic alcohol, a triol and a hydroxy polyunsaturated fatty acid.
References
1. Serhan, C.N., Hong, S., Gronert, K., et al. Resolvins: A family of bioactive products of ω-