2-O-benzoyl-3-O-t-butyldiphenylsilyl-L-threonolactone
2-O-benzoyl-3-O-t-butyldiphenylsilyl-L-threonolactone Basic information
- Product Name:
- 2-O-benzoyl-3-O-t-butyldiphenylsilyl-L-threonolactone
- Synonyms:
-
- 2-O-benzoyl-3-O-t-butyldiphenylsilyl-L-threonolactone
- 2-O-Benzoyl-3-O-tert-butyldiphenylsilyl-L-threonolactone
- 2(3H)-Furanone, 3-(benzoyloxy)-4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]dihydro-, (3R,4S)-
- 4-[(tert-Butyldiphenylsilyl)oxy]-2-oxo-3-tetrahydrofuryl (3R,4S)-Benzoate
- CAS:
- 1446785-28-9
- MF:
- C27H28O5Si
- MW:
- 460.59
- Mol File:
- 1446785-28-9.mol
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2-O-benzoyl-3-O-t-butyldiphenylsilyl-L-threonolactone Chemical Properties
- Boiling point:
- 557.3±50.0 °C(Predicted)
- Density
- 1.19±0.1 g/cm3(Predicted)
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2-O-benzoyl-3-O-t-butyldiphenylsilyl-L-threonolactone Usage And Synthesis
Uses
2-O-Benzoyl-3-O-t-butyldiphenylsilyl-L-threono lactone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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