JNJ 10181457 dihydrochloride
JNJ 10181457 dihydrochloride Basic information
- Product Name:
- JNJ 10181457 dihydrochloride
- Synonyms:
-
- JNJ-10181457 (hydrochloride)
- 4-[3-[4-[Piperidinyl]but-1-ynyl]benzyl]morpholine dihydrochloride
- CAS:
- 544707-20-2
- MF:
- C20H29ClN2O
- MW:
- 348.92
- Mol File:
- 544707-20-2.mol
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JNJ 10181457 dihydrochloride Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- Soluble to 100 mM in water and to 25 mM in ethanol
- form
- Powder
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JNJ 10181457 dihydrochloride Usage And Synthesis
Uses
JNJ 10181457 Dihydrochloride is an inhibitor of the histamine H3 receptor.
in vivo
JNJ-10181457 (10 mg/kg, i.p., 60 min) reverses Imetit (HY-101173, 3 mg/kg, s.c.)-induced water licking in rats and Scopolamine (HY-N0296, 0.06 mg/kg, i.p.)-induced increasing of incorrect responding in DNMTP task[1].
IC 50
H3 Receptor
JNJ 10181457 dihydrochlorideSupplier
Shanghai EFE Biological Technology Co., Ltd.
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Shanghai Hongye Biotechnology Co. Ltd
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- 400-9205774
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TargetMol Chemicals Inc.
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- +1-781-999-5354; +17819995354
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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- 18818260767
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TargetMol Chemicals Inc.
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- marketing@tsbiochem.com