Olanexidine-008-HCl Chemical Properties

storage temp. 

Store at -20°C

solubility 

DMSO: 82 mg/mL (196.27 mM);Ethanol: 82 mg/mL (196.27 mM)

Water Solubility 

Water: Insoluble

Olanexidine-008-HCl Usage And Synthesis

Uses

Olanexidine hydrochloride semihydrate is an antibacterial agent. Olanexidine hydrochloride semihydrate is active against a wide range of bacteria, imcluding both Gram-positive and Gram-negative bacteria Olanexidine hydrochloride semihydrate is also an antiseptic. Olanexidine hydrochloride semihydrate can be used in the research of infection and inflammation[1][2][3].

Definition

ChEBI: Olanexidine hydrochloride hydrate is a dichlorobenzene.

References

[1] Hagi A, et al. Bactericidal Effects and Mechanism of Action of Olanexidine Gluconate, a New Antiseptic. Antimicrob Agents Chemother. 2015 Aug;59(8):4551-9. DOI:10.1128/AAC.05048-14
[2] Nii T, Yumoto H, Hirota K, Miyake Y. Anti-inflammatory effects of olanexidine gluconate on oral epithelial cells. BMC Oral Health. 2019 Nov 8;19(1):239. DOI:10.1186/s12903-019-0932-0
[3] Imai K, et al. Disinfection efficacy and mechanism of olanexidine gluconate against norovirus. Am J Infect Control. 2022 Jul;50(7):764-771. DOI:10.1016/j.ajic.2021.11.020
[4] Nakata H, et al. Effects of olanexidine gluconate on preoperative skin preparation: an experimental study in cynomolgus monkeys. J Med Microbiol. 2017 May;66(5):678-685. DOI:10.1099/jmm.0.000462