4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide
4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide Basic information
- Product Name:
- 4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide
- Synonyms:
-
- 4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide
- APN-?NH2
- RUN92619
- Butanamide, 4-amino-N-[4-(2-cyanoethynyl)phenyl]-
- CAS:
- 1539292-61-9
- MF:
- C13H13N3O
- MW:
- 227.26
- Mol File:
- 1539292-61-9.mol
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4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide Chemical Properties
- Density
- 1.19±0.1 g/cm3(Predicted)
- pka
- 14.23±0.70(Predicted)
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4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide Usage And Synthesis
Description
APN-amine is a heterobifunctional linker containing an APN moiety with exquisite chemoselectivity for cysteine and an amine group. The superior stability of APN-cysteine conjugates in aqueous media, human plasma, and living cells makes this new thiol-click reaction a promising methodology for applications in bioconjugation.
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