tert-butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate
tert-butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate Basic information
- Product Name:
- tert-butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate
- Synonyms:
-
- tert-butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate
- APN-C3-NH-Boc
- AUN 92608
- Carbamic acid, N-[4-[[4-(2-cyanoethynyl)phenyl]amino]-4-oxobutyl]-, 1,1-dimethylethyl ester
- CAS:
- 1539292-60-8
- MF:
- C18H21N3O3
- MW:
- 327.38
- Mol File:
- 1539292-60-8.mol
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tert-butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate Chemical Properties
- Density
- 1.17±0.1 g/cm3(Predicted)
- pka
- 12.66±0.46(Predicted)
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tert-butyl 3-(4-(2-cyanoethynyl)phenylcarbamoyl)propylcarbamate Usage And Synthesis
Description
APN-NH-Boc is a heterobifunctional linker containing an APN moiety with exquisite chemoselectivity for cysteine and Boc group. The superior stability of APN-cysteine conjugates in aqueous media, human plasma, and living cells makes this new thiol-click reaction a promising methodology for applications in bioconjugation.
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