AWZ1066S
AWZ1066S Basic information
- Product Name:
- AWZ1066S
- Synonyms:
-
- AWZ1066S
- AWZ1066S;AWZ-1066S;AWZ 1066S
- Pyrido[2,3-d]pyrimidin-4-amine, 2-[(3S)-3-methyl-4-morpholinyl]-N-[[2-(trifluoromethyl)-3-pyridinyl]methyl]-
- 2-[(3S)-3-Methyl-4-morpholinyl]-N-[[2-(trifluoromethyl)-3-pyridinyl]methyl]pyrido[2,3-d]pyrimidin-4-amine
- oral,Inhibitor,anti-Wolbachia,Onchocerciasis (river blindness),CYP3A4,AWZ1066S,Parasite,AWZ-1066S,CYP2C9,tropical diseases,inhibit,lymphatic filariasis (elephantiasis)
- CAS:
- 2239272-16-1
- MF:
- C19H19F3N6O
- MW:
- 404.39
- Mol File:
- 2239272-16-1.mol
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AWZ1066S Chemical Properties
- storage temp.
- Store at -20°C
- solubility
- DMSO : 125 mg/mL (309.11 mM; Need ultrasonic)
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AWZ1066S Usage And Synthesis
Biological Activity
AWZ1066S is a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis, with an EC50 of 2.5 nM in cell assay[1].
References
[1]. Hong WD, et al. AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis. Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1414-1419.
AWZ1066SSupplier
Shanghai Lollane Biological Technology Co.,Ltd.
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- 021-52996696，15000506266 15000506266
ShangHai Biochempartner Co.,Ltd
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- 17754423994 17754423994
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Shanghai Chaolan Chemical Technology Center
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- QQ:65489617 15618227136
- info@SuperLan-chem.com
Shanghai SuperLan Chemcial Technique Centre
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- 021-2022843681 15618226720
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Chuzhou KeMail Chemical Technology Co., Ltd
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- 0550-5196001 15000891977
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