(D-TRP2,7,9)-SUBSTANCE P
(D-TRP2,7,9)-SUBSTANCE P Basic information
- Product Name:
- (D-TRP2,7,9)-SUBSTANCE P
- Synonyms:
-
- (D-TRP2,7,9)-SUBSTANCE P
- H-ARG-D-TRP-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-MET-NH2
- ARG-D-TRP-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-MET-NH2
- L-Methioninamide, L-arginyl-D-tryptophyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-D-tryptophyl-L-phenylalanyl-D-tryptophyl-L-leucyl- (9CI)
- CAS:
- 100930-11-8
- MF:
- C80H109N21O13S
- MW:
- 1604.92
- Mol File:
- 100930-11-8.mol
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(D-TRP2,7,9)-SUBSTANCE P Chemical Properties
- Density
- 1.44±0.1 g/cm3(Predicted)
- storage temp.
- -15°C
- pka
- 13.27±0.46(Predicted)
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(D-TRP2,7,9)-SUBSTANCE P Usage And Synthesis
Uses
[D-Trp2,7,9] Substance P is a tachykinin (Neurokinin Receptor) antagonist with Ki values of 1 μM, 1.3 μM, and ~9 μM for NK-1, NK-2,and NK-3 receptor, respectively[1].
IC 50
NK1: 1 μM (Ki); NK2: 1.3 μM (Ki); NK3: ~9 μM (Ki)
References
[1] S H Buck, et al. Agonist and antagonist binding to tachykinin peptide NK-2 receptors. Life Sci. 1988;42(26):2701-8. DOI:10.1016/0024-3205(88)90246-9
(D-TRP2,7,9)-SUBSTANCE PSupplier
GL Biochem (Shanghai) Ltd
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- 21-61263452 13641803416
- ymbetter@glbiochem.com
Nanjing Peptide Biotech Ltd.
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- 025-58361106-805 15951641583
- zhao.xu@njpeptide.com
Chengdu Youngshe Chemical Co., Ltd.
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- +86-17380623303
- Caroline@youngshechem.com
Hangzhou Peptidego Biotech Co.,Ltd.
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- 0571-87213919
- Eric@peptidego.com
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
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- meitaochem@126.com
- meitaochem@126.com