DIMETHYL-(2,3-DIMETHYL-2-BUTYL)SILYL TRIFLUOROMETHANESULFONATE Chemical Properties

Boiling point:

53-54 °C0.6 mm Hg(lit.)

Density 

1.16 g/mL at 20 °C(lit.)

refractive index 

n20/D 1.405

Flash point:

85 °C

solubility 

CH2Cl2, CHCl3, Et2O, THF (can result in ring opening of THF), DMF; reacts with alcohols and water.

Safety Information

Hazard Codes 

C

Risk Statements 

14-34

Safety Statements 

26-27-36/37/39-45

RIDADR 

UN 3265 8/PG 2

WGK Germany 

3

F 

10-21

HazardClass 

8

PackingGroup 

III

MSDS

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DIMETHYL-(2,3-DIMETHYL-2-BUTYL)SILYL TRIFLUOROMETHANESULFONATE Usage And Synthesis

Physical properties

clear light yellow liquid, bp 40–42 °C/0.15 Torr, 53–54 °C/0.6 mmHg; d = 1.16 g mL?1 at 20 °C; n20 D 1.405.

Uses

Silylation reagent used to introduce the dimethylthexylsilyl (TDS) group; complexation reagent to activate electrophiles. Dimethylthexylsilyl trifluoromethanesulfonate (TDSOTf) is generally used as a bulky silylation reagent.

Preparation

Dimethylthexylsilyl chloride and trifluoromethanesulfonic acid are heated to 60°Cfor 4–5 h and the resulting silyl ester is isolated by distillation.

DIMETHYL-(2,3-DIMETHYL-2-BUTYL)SILYL TRIFLUOROMETHANESULFONATE(103588-79-0)Related Product Information

• Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester
• TRIMETHYLSILYL METHANESULFONATE
• TrimethylSilyl Trifluoromethanesulfonate
• DIMETHYLISOPROPYLSILANE
• T-BUTYLDIMETHYLSILANE
• Trifluoromethanesulfonic acid
• TERT-BUTYLDIMETHYLSILANOL
• DIMETHYL-(2,3-DIMETHYL-2-BUTYL)SILYL TRIFLUOROMETHANESULFONATE