PD 168 077 MALEATE
PD 168 077 MALEATE Basic information
- Product Name:
- PD 168 077 MALEATE
- Synonyms:
-
- n-[[4-(2-cyanophenyl)-1-piperazinyl]methyl]-3-methylbenzamide maleate salt
- pd 168,077 maleate salt
- N-[[4-(2-Cyanophenyl)-1-piperazinyl]methyl]-3-methyl-benzamide
- N-((4-(2-CYANOPHENYL)PIPERAZIN-1-YL)METHYL)-3-METHYLBENZAMIDE MALEATE
- N-[[4-(2-cyanophenyl)piperazin-1-yl]methyl]-3-methylbenzamide
- Benzamide, N-[[4-(2-cyanophenyl)-1-piperazinyl]methyl]-3-methyl-
- 077
- PD 168
- CAS:
- 190383-31-4
- MF:
- C20H22N4O
- MW:
- 334.41
- Product Categories:
-
- Dopamine receptor
- Mol File:
- 190383-31-4.mol
More
Less
PD 168 077 MALEATE Chemical Properties
- Boiling point:
- 554.6±50.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- solubility
- DMSO: >10 mg/mL
- form
- powder
- pka
- 14.89±0.46(Predicted)
- color
- white
- InChIKey
- NAEUGRPISCANHO-BTJKTKAUSA-N
- SMILES
- [H]\C(=C(/[H])C(O)=O)C(O)=O.Cc1cccc(c1)C(=O)NCN2CCN(CC2)c3ccccc3C#N
More
Less
Safety Information
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- Storage Class
- 11 - Combustible Solids
More
Less
PD 168 077 MALEATE Usage And Synthesis
Uses
The dopamine receptors play important role in cognition, memory, learning, and motor control (1). These receptors have been implicated as a therapeutic target for many psychiatric and neurological disorders. PD 168077 is a D4 dopamine receptor agonist and can be used to study ligand-receptor interactions of dopamine receptors (2).
Biological Activity
Selective D4 dopamine receptor agonist.
in vivo
PD-168077 (0.2-25.0 mg/kg) dose-dependently induces locomotion, which takes an unusual and characteristic ”shuffling” form with uncoordinated movements together with yawning, and episodes of myoclonic jerking; grooming, and rearing are reduced[1].
PD 168 077 MALEATESupplier
Chengdu YouSuo Biotechnology Limited
- Tel
- 13693449011
- 83948782@qq.com
Sigma-Aldrich
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
Tianjin Kailiqi Biotechnology Co., Ltd.
- Tel
- 15076683720
- klq@cw-bio.com
Amadis Chemical Company Limited
- Tel
- 571-89925085
- sales@amadischem.com
Nanjing KaiMubo Pharmaceutical Co., Ltd.
- Tel
- 025-66162170