4-FLUORO-3-NITROBENZYL ALCOHOL 96 Chemical Properties

Melting point:

39-44 °C (lit.)

Boiling point:

333.7±27.0 °C(Predicted)

Density 

1.434

Flash point:

230 °F

storage temp. 

Sealed in dry,Room Temperature

pka

13.37±0.10(Predicted)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36

Safety Statements 

26

WGK Germany 

3

HS Code 

2906290090

4-FLUORO-3-NITROBENZYL ALCOHOL 96 Usage And Synthesis

Uses

4-Fluoro-3-nitrobenzyl Alcohol is used as a reagent in the preparation of EW-7197 (E950000) which is a highly potent orally bioavailable inhibitor of TGF-β type I receptor kinase that is used in cancer treatment as an immunotherapeutic or antifibrotic agent.

Uses

4-Fluoro-3-nitrobenzyl alcohol may be used in the synthesis of 4-fluoro-3-nitrobenzyl chloride.

General Description

4-Fluoro-3-nitrobenzyl alcohol can be prepared from the reaction between borane (in THF) and 4-fluoro-3-nitrobenzoic acid (in THF) at 0°C.

4-FLUORO-3-NITROBENZYL ALCOHOL 96(20274-69-5)Related Product Information

• 4-Fluoro-3-nitrobenzyl bromide
• 4-Fluoro-3-nitrobenzoic acid
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