STYLOPINE, (-)-(RG)(CALL) Chemical Properties

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Cryst.

InChI

InChI=1S/C19H17NO4/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14/h1-2,6-7,15H,3-5,8-10H2

InChIKey

UXYJCYXWJGAKQY-UHFFFAOYSA-N

SMILES

O1C([H])([H])OC2C([H])=C([H])C3=C(C1=2)C([H])([H])N1C([H])([H])C([H])([H])C2=C([H])C4=C(C([H])=C2C1([H])C3([H])[H])OC([H])([H])O4

STYLOPINE, (-)-(RG)(CALL) Usage And Synthesis

Description

Tetrahydrocoptisine is an active anti-inflammatory constituent by inhibition of TNF-α, IL-6 and NO production possibly via down-regulation of NF-κB activation, phospho-ERK1/2 and phospho-p38MAPK signal pathways.Tetrahydrocoptisine has gastroprotective activity, is attributed to reducing NO production and adjusting the pro-inflammatory cytokine, inhibited neutrophil accumulation and NF-κB expression.

STYLOPINE, (-)-(RG)(CALL)(7461-02-1)Related Product Information

• COPTISINE