3-(PYRROLIDIN-1-YLMETHYL)BENZOIC ACID HYDROCHLORIDE Chemical Properties

Melting point:

168 °C

storage temp. 

Inert atmosphere,Room Temperature

Safety Information

Risk Statements 

41

Safety Statements 

26-39

3-(PYRROLIDIN-1-YLMETHYL)BENZOIC ACID HYDROCHLORIDE Usage And Synthesis

Synthesis

Methyl 3-(1-pyrrolidinylmethyl)benzoate (800 mg, 3.6 mmol) was used as a raw material and dissolved in 25% aqueous hydrochloric acid (15 mL). The reaction mixture was stirred at 90 °C for 4 hours. Upon completion of the reaction, the solvent was removed by evaporation to afford 3-(1-pyrrolidinylmethyl)benzoic acid hydrochloride as a brown oil in quantitative yield. The resulting product was used directly in the subsequent reaction without further purification.

References

[1] Patent: WO2007/68637, 2007, A1. Location in patent: Page/Page column 50

3-(PYRROLIDIN-1-YLMETHYL)BENZOIC ACID HYDROCHLORIDE(887922-93-2)Related Product Information

• [3-(PYRROLIDIN-1-YLMETHYL)PHENYL]METHANOL
• 5-TMR-PLSRTLSVAAKK-NH2
• 3-(PYRROLIDIN-1-YLMETHYL)BENZOIC ACID HYDROCHLORIDE
• 3-(pyrrolidin-1-ylmethyl)benzoic acid
• 5-TMR-PLSRTLSVSS-NH2