O6-[4-(TRIFLUOROACETAMIDOMETHYL)BENZYL]GUANINE
O6-[4-(TRIFLUOROACETAMIDOMETHYL)BENZYL]GUANINE Basic information
- Product Name:
- O6-[4-(TRIFLUOROACETAMIDOMETHYL)BENZYL]GUANINE
- Synonyms:
-
- O6-[4-(TRIFLUOROACETAMIDOMETHYL)BENZYL]GUANINE
- N-[4-(2-Amino-9H-purin-6-yloxymethyl)-benzyl]-2,2,2-trifluoroacetamide
- Acetamide, N-[[4-[[(2-amino-1H-purin-6-yl)oxy]methyl]phenyl]methyl]-2,2,2-trifluoro-
- Inhibitor,MicroRNA,PIN1 inhibitor API 1,PIN1 inhibitor API-1,PIN1 inhibitor API1,inhibit,PIN-1 inhibitor API-1,miRNA
- N-(4-(((2-Amino-1H-purin-6-yl)oxy)methyl)benzyl)-2,2,2-trifluoroacetamide
- PIN1 inhibitor API-1, 10 mM in DMSO
- PIN1 inhibitor API-1 ，S6893
- CAS:
- 680622-70-2
- MF:
- C15H13F3N6O2
- MW:
- 366.3
- Product Categories:
-
- Amines
- Bases & Related Reagents
- Cross Linking Reagents
- Heterocycles
- Nucleotides
- Chemical Amines
- Mol File:
- Mol File
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O6-[4-(TRIFLUOROACETAMIDOMETHYL)BENZYL]GUANINE Chemical Properties
- Melting point:
- 211-213?C
- Density
- 1.525±0.06 g/cm3(Predicted)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 9.52±0.10(Predicted)
- color
- White to Off-White
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O6-[4-(TRIFLUOROACETAMIDOMETHYL)BENZYL]GUANINE Usage And Synthesis
Chemical Properties
White Solid
Uses
O6-[4-(Trifluoroacetamidomethyl)benzyl]guanine (cas# 680622-70-2) is a specific Pin1 (peptidyl-prolyl cis-trans isomerase NIMA-interacting 1) inhibitor.
in vivo
PIN1 inhibitor API-1 suppresses tumor growth in mice by up-regulating mature miRNA biogenesis[1].
O6-[4-(TRIFLUOROACETAMIDOMETHYL)BENZYL]GUANINESupplier
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