ETHYL 3,4-DIHYDROXYCINNAMATE Chemical Properties

Melting point:

147～151℃

Boiling point:

148-149 °C

Density 

1.271±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

pka

8.71±0.18(Predicted)

form 

Off-white to brown solid.

color 

White to off-white

biological source

plant

LogP

2.418 (est)

Safety Information

Hazard Codes 

Xn

Risk Statements 

36/37/38-22

Safety Statements 

26-36

MSDS

• Language:English Provider:ALFA

ETHYL 3,4-DIHYDROXYCINNAMATE Usage And Synthesis

Uses

Ethyl 3,4-dihydroxycinnamate shows anti-inflammatory, immunomodulatory, and anti-carcinogenic properties. It is a potent and specific inhibitor of NF-κB and its downstream inflammatory mediators: NOS2 (inducible nitric oxide synthase; NOS; NOS II), Cox-2 (cyclooxygenase-2), and prostaglandin E2 (PGE2). Ethyl 3,4-Dihydroxycinnamate prevents DNA single-strand breaks caused by H2O2.

Definition

ChEBI: Ethyl trans-caffeate is an ethyl ester resulting from the formal condensation of the carboxy group of trans-caffeic acid with ethanol. It has a role as an anti-inflammatory agent and an antineoplastic agent. It is an alkyl caffeate ester and an ethyl ester. It is functionally related to a trans-caffeic acid.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biological Activity

Ethyl dihydroxycinnamate exhibits potent cytotoxicity, inhibits COX-2 and P-hydroxybenzoic acid, both involved in inflammation and cytokine synthesis. It demonstrates antibacterial efficacy against MRSA and Bacillus subtilis and inhibits cancer cell growth, countering tumor formation.

ETHYL 3,4-DIHYDROXYCINNAMATE(66648-50-8)Related Product Information

• Isobutyl cinnamate
• Caffeic acid
• Ethyl cinnamate
• ethyl 2,5-dihydroxycinnamate