5-ETHOXY-2-PYRROLIDINONE Chemical Properties

Melting point:

50-51 °C

Boiling point:

100 °C(Press: 3 Torr)

Density 

1.06±0.1 g/cm3(Predicted)

solubility 

Chloroform (Sparingly), Methanol (Slightly)

form 

Solid

pka

14.90±0.40(Predicted)

color 

Off-White to Pale Yellow

5-ETHOXY-2-PYRROLIDINONE Usage And Synthesis

Uses

5-Ethoxy-2-pyrrolidone is an intermediate in the synthesis of rac-Vigabatrin (V253005), a novel antiepileptic drug. Antidepressant; antipsychotic; anxiolytic.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 22, p. 2999, 1974 DOI: 10.1248/cpb.22.2999

5-ETHOXY-2-PYRROLIDINONE(39662-63-0)Related Product Information

• (+-)-1-Benzoyl-5-(heptyloxy)-2-pyrrolidinone
• (3S-CIS)-(+)-TETRAHYDRO-3,7A-DIPHENYLPYRROLO[2,1-B]OXAZOL-5(6H)-ONE
• (3R-CIS)-(-)-3-PHENYLTETRAHYDROPYRROLO-[2,1-B]-OXAZOL-5(6H)-ONE
• (3S)-3-ISOPROPYL BICYCLIC LACTAM
• (3S-CIS)-7A-METHYL-3-PHENYLTETRAHYDROPYRROLO[2,1-B]OXAZOL-5(6H)-ONE
• (3S,7AR)-3-ISOPROPYL-7A-PHENYL BICYCLIC LACTAM
• (3R-CIS)-(-)-3-ISOPROPYL-7A-METHYLTETRAHYDROPYRROLO[2,1-B]OXAZOL-5(6H)-ONE
• (3R-CIS)-7A-METHYL-3-PHENYLTETRAHYDROPYRROLO[2,1-B]OXAZOL-5(6H)-ONE
• (3S-CIS)-(-)-3-PHENYLTETRAHYDROPYRROLO-[2,1-B]-OXAZOL-5(6H)-ONE
• (3S,7AR)-3-T-BUTYL-7A-METHYL BICYCLIC LACTAM
• (3R-CIS)-3,7A-DIPHENYLTETRAHYDROPYRROLO-[ 2,1-B]OXAZOL-5(6H)-ONE
• (+-)-5-(Heptyloxy)-1-(phenylmethyl)-2-pyrrolidinone
• (3R,7AS)-3-ISOPROPYL-7A-PHENYL BICYCLIC LACTAM
• (+-)-5-(Octyloxy)-1-((4-(trifluoromethyl)phenyl)methyl)-2-pyrrolidinon e
• 2-Pyrrolidinone, 5-(octyloxy)-1-(phenylmethyl)-, (+-)-
• (+-)-5-(Hexyloxy)-1-(phenylmethyl)-2-pyrrolidinone
• (+-)-5-(Pentyloxy)-1-(phenylmethyl)-2-pyrrolidinone