IFLAB-BB F2124-0088 Chemical Properties

Boiling point:

340.8±42.0 °C(Predicted)

Density 

1.309±0.06 g/cm3(Predicted)

storage temp. 

2-8°C(protect from light)

pka

2.73±0.10(Predicted)

IFLAB-BB F2124-0088 Usage And Synthesis

Synthesis

General procedure: A mixed solution of 5-amino-4,6-dichloropyrimidine (1.0 mmol), triethylamine (1.0 mmol), ethanol (4.3 mL) and n-propylamine (2.5 mmol) was placed in an autoclave reactor, heated to a specified temperature and kept for a period of time. After completion of the reaction, the volatile components were evaporated under reduced pressure and the crude product was purified according to a specific method to obtain the target compound 6-chloro-N4-propyl-4,5-pyrimidinediamine.

References

[1] European Journal of Medicinal Chemistry, 2018, vol. 151, p. 199 - 213
[2] Journal of Medicinal Chemistry, 1997, vol. 40, # 20, p. 3207 - 3216
[3] Patent: WO2014/75393, 2014, A1. Location in patent: Page/Page column 175
[4] Organic Letters, 2017, vol. 19, # 23, p. 6360 - 6363

IFLAB-BB F2124-0088(195252-56-3)Related Product Information

• IFLAB-BB F2124-0129
• 4-CHLORO-6-PYRROLIDIN-1-YL-PYRIMIDIN-5-YLAMINE
• 4-CHLORO-6-(3,4-DIHYDRO-1(2H)-QUINOLINYL)-5-PYRIMIDINAMINE
• 4-CHLORO-5-NITRO-6-(1-PYRROLIDINYL)PYRIMIDINE
• 6-chloro-N4-cyclopentylpyrimidine-4,5-diamine
• IFLAB-BB F2124-0085
• 1-(6-CHLORO-5-NITRO-4-PYRIMIDINYL)-1,2,3,4-TETRAHYDROQUINOLINE
• N4-BUTYL-6-CHLORO-PYRIMIDINE-4,5-DIAMINE
• IFLAB-BB F2124-0139
• IFLAB-BB F2124-0096
• IFLAB-BB F2124-0130
• 4-CHLORO-6-PIPERIDIN-1-YL-PYRIMIDIN-5-YLAMINE
• 6-chloro-N4-cyclopropylpyrimidine-4,5-diamine
• IFLAB-BB F2124-0088
• IFLAB-BB F2124-0089
• AKOS BBS-00003139
• IFLAB-BB F2124-0086
• AKOS BBS-00003136