Basic information Safety Supplier Related

AC-LEHD-CMK

Basic information Safety Supplier Related

AC-LEHD-CMK Basic information

Product Name:
AC-LEHD-CMK
Synonyms:
  • CASPASE-9 INHIBITOR III
  • AC-LEU-GLU-HIS-ASP-CHLOROMETHYLKETONE
  • AC-LEU-GLU-HIS-ASP-CMK
  • AC-LEHD-CMK
  • L-Histidinamide, N-acetyl-L-leucyl-L-α-glutamyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-
  • Caspase-9 Inhibitor III(Ac-LEHD-CMK)
  • N-Acetyl-L-leucyl-L-α-glutamyl-N-[(1S)-1-(carboxymethyl)-3-chloro-2-oxopropyl]-L-histidinamide
  • (4S,7S,10S,13S)-10-((1H-Imidazol-4-yl)methyl)-7-(2-carboxyethyl)-13-(2-chloroacetyl)-4-isobutyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid
CAS:
403848-57-7
MF:
C24H35ClN6O9
MW:
587.02
Product Categories:
  • Caspase/Related Products
Mol File:
Mol File
More
Less

AC-LEHD-CMK Chemical Properties

Boiling point:
1113.4±65.0 °C(Predicted)
Density 
1.362±0.06 g/cm3(Predicted)
storage temp. 
-15°C
pka
3.91±0.19(Predicted)
form 
Powder
color 
White to off-white
Water Solubility 
water: 1mg/mL
DMSO: 5mg/mL
More
Less

AC-LEHD-CMK Usage And Synthesis

Uses

A potent and irreversible inhibitor of caspase-9

Biological Activity

Cell permeable: yes', 'Primary Target
caspase-9', 'Product does not compete with ATP.', 'Reversible: no', 'Target IC50: 70 nM against caspase-9

IC 50

Caspase-9

AC-LEHD-CMKSupplier

GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Email
ymbetter@glbiochem.com
VDM Biochemicals
Tel
0330-2528181
Email
sales@vdmbio.com
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Email
info@chemlin.com.cn
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com