(5-METHYL-1H-PYRAZOL-3-YL)-(2-PHENYLQUINAZOLIN-4-YL)AMINE
(5-METHYL-1H-PYRAZOL-3-YL)-(2-PHENYLQUINAZOLIN-4-YL)AMINE Basic information
- Product Name:
- (5-METHYL-1H-PYRAZOL-3-YL)-(2-PHENYLQUINAZOLIN-4-YL)AMINE
- Synonyms:
-
- GSK-3 INHIBITOR XIII
- (5-METHYL-1H-PYRAZOL-3-YL)-(2-PHENYLQUINAZOLIN-4-YL)AMINE
- 4-Quinazolinamine, 5,6,7,8-tetrahydro-N-(5-methyl-1H-pyrazol-3-yl)-2-phenyl-
- GSK3i XIII
- Glycogen synthase kinase 3,Glycogen synthase kinase-3,ATP-competitive,GSK3i XIII,Inhibitor,GSK-3 Inhibitor XIII,GSK-3i XIII,GSK-3,inhibit
- N-(5-methyl-1H-pyrazol-3-yl)-2-phenyl-5,6,7,8-tetrahydroquinazolin-4-amine
- GSK3i XIII, 10 mM in DMSO
- CAMK1D-IN-1
- CAS:
- 404828-08-6
- MF:
- C18H19N5
- MW:
- 305.38
- Mol File:
- 404828-08-6.mol
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(5-METHYL-1H-PYRAZOL-3-YL)-(2-PHENYLQUINAZOLIN-4-YL)AMINE Chemical Properties
- Boiling point:
- 451.8±45.0 °C(Predicted)
- Density
- 1.262±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF:0.25(Max Conc. mg/mL);0.83(Max Conc. mM)
DMSO:0.15(Max Conc. mg/mL);0.5(Max Conc. mM) - form
- White crystalline solid.
- pka
- 13.78±0.10(Predicted)
- color
- white
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(5-METHYL-1H-PYRAZOL-3-YL)-(2-PHENYLQUINAZOLIN-4-YL)AMINE Usage And Synthesis
Uses
GSK-3 Inhibitor XIII is a potent and ATP-binding site inhibitor of GSK-3.
Biological Activity
Cell permeable: no', 'Primary Target
GSK-3', 'Product does not compete with ATP.', 'Reversible: no', 'Target Ki: 24 nM against GSK-3
(5-METHYL-1H-PYRAZOL-3-YL)-(2-PHENYLQUINAZOLIN-4-YL)AMINESupplier
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