2-(diethylamino)ethyl 4-ethoxybenzoate hydrochloride
2-(diethylamino)ethyl 4-ethoxybenzoate hydrochloride Basic information
- Product Name:
- 2-(diethylamino)ethyl 4-ethoxybenzoate hydrochloride
- Synonyms:
-
- 2-(diethylamino)ethyl 4-ethoxybenzoate hydrochloride
- 4-Ethoxybenzoic acid,2-[diethylamino] ethyl ester
- Parethoxycaine hydrochloride
- β-Diethylaminoethyl-p-ethoxybenzoate
- Parethoxycaine
- 4-ethoxybenzoic acid 2-diethylaminoethyl ester hydrochloride
- Diethoxin
- Parethoxycaine hydrochloride, 10 mM in DMSO
- CAS:
- 136-46-9
- MF:
- C15H23NO3
- MW:
- 265.34802
- EINECS:
- 2052464
- Mol File:
- 136-46-9.mol
2-(diethylamino)ethyl 4-ethoxybenzoate hydrochloride Chemical Properties
- Melting point:
- 172.5-173.5°
2-(diethylamino)ethyl 4-ethoxybenzoate hydrochloride Usage And Synthesis
Uses
Parethoxycaine hydrochloride is an anesthetic with nerve conduction blocking activity. Parethoxycaine hydrochloride exhibits non-selective inhibitory effects on responses to various stimulants in rat vas deferens and guinea pig ileum muscles. Parethoxycaine hydrochloride has an enhanced effect on the action of norepinephrine, and its methyl bromide derivative also exhibits the same properties on the action of norepinephrine and potassium ions. Derivatives of parethoxycaine hydrochloride have significant effects on calcium dose-response curves, displaying different tissue and stimulant selectivities. The mechanism of action of Parethoxycaine hydrochloride involves the regulation of calcium transport processes[1].
brand name
Intracaine Hydrochloride (BristolMyers Squibb).
References
[1] Calcium antagonists and contractile responses in rat vas deferens and guinea pig ileal smooth muscle
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