sulfadicramide
sulfadicramide Basic information
- Product Name:
- sulfadicramide
- Synonyms:
-
- sulfadicramide
- N-[(4-Aminophenyl)sulfonyl]-3-methyl-2-butenamide
- N-(4-aminophenyl)sulfonyl-3-methyl-but-2-enamide
- N-(4-aminophenyl)sulfonyl-3-methylbut-2-enamide
- N-(4-azanylphenyl)sulfonyl-3-methyl-but-2-enamide
- 2-ButenaMide, N-[(4-aMinophenyl)sulfonyl]-3-Methyl-
- CAS:
- 115-68-4
- MF:
- C11H14N2O3S
- MW:
- 254.31
- EINECS:
- 204-099-3
- Mol File:
- 115-68-4.mol
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sulfadicramide Chemical Properties
- Melting point:
- 184-185°
- Density
- 1.3010 (rough estimate)
- refractive index
- 1.5650 (estimate)
- Water Solubility
- 261mg/L(20 ºC)
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sulfadicramide Usage And Synthesis
Definition
ChEBI: Sulfadicramide is a member of benzenes and a sulfonamide.
brand name
Ingamid ophtal;Irgamid.
World Health Organization (WHO)
Sulfadicramide, a sulfonamide anti-infective agent, was introduced in 1942 for the treatment of bacterial infections. The importance of sulfonamides has subsequently decreased as a result of increasing resistance and their replacement by antibiotics which are generally more active and less toxic. The sulfonamides are known to cause serious adverse effects such as renal toxicity, sometimes fatal exfoliative dermatitis and erythema multiforma and dangerous adverse reactions affecting blood formation such as agranulocytosis and haemolytic or aplastic anaemia. Sulfadicramide is still used in some countries as a 15% ointment for application to the eye.