Befunolol hydrochloride Chemical Properties

Melting point:

163°

form 

Liquid eye medication

Safety Information

Toxicity

LD50 oral in rabbit: 400mg/kg

Befunolol hydrochloride Usage And Synthesis

Description

Befunolol hydrochloride is the newest of the 8-adrenergic blockers to be introduced for the treatment of glaucoma. It is reportedly devoid of intrinsic sympathomimetic activity, with lower membrane-stabilizing activity than propranolol.

Originator

Kalcen (Japan)

brand name

BENTOX

Safety Profile

Poison by intravenous andintraperitoneal routes. Moderately toxic by ingestion andsubcutaneous routes. An experimental teratogen. Otherexperimental reproductive effects. When heated todecomposition it emits toxic fumes of NOx and HCl. Abeta-adrenergi

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