11-(PIPERAZIN-1-YL)DIBENZO[B,F][1,4]THIAZEPINE
11-(PIPERAZIN-1-YL)DIBENZO[B,F][1,4]THIAZEPINE Basic information
- Product Name:
- 11-(PIPERAZIN-1-YL)DIBENZO[B,F][1,4]THIAZEPINE
- Synonyms:
-
- 11-(piperazin-1-yl)dibenzo[b,f][1,4]thiazepine
- 11-Piperazinodibenzo[b,f][1,4]thiazepine
- N-Desalkylquetiapine
- Norquetiapine
- 11-(Piperazin-1-yl)
- 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine
- 2-(Piperazin-1-yl)dithiazepin
- 7-chloro-2-(2-methylphenyl)-3,1-benzoxazin-4-one
- CAS:
- 5747-48-8
- MF:
- C17H17N3S
- MW:
- 295.4
- Product Categories:
-
- Heterocycles
- Intermediates & Fine Chemicals
- Metabolites & Impurities
- Pharmaceuticals
- Mol File:
- 5747-48-8.mol
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11-(PIPERAZIN-1-YL)DIBENZO[B,F][1,4]THIAZEPINE Chemical Properties
- Boiling point:
- 465.2±55.0 °C(Predicted)
- Density
- 1.30
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMF: 16 mg/mL; DMSO: 3 mg/mL; Ethanol: 5 mg/mL; PBS (pH 7.2): 0.25 mg/mL
- form
- A solid
- pka
- 8.55±0.10(Predicted)
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11-(PIPERAZIN-1-YL)DIBENZO[B,F][1,4]THIAZEPINE Usage And Synthesis
Chemical Properties
Pale-Yellow Solid
Uses
11-(Piperazin-1-yl)dibenzo[b,f][1,4]thiazepine is a metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic.
Definition
ChEBI: Norquetiapine is a dibenzothiazepine.
11-(PIPERAZIN-1-YL)DIBENZO[B,F][1,4]THIAZEPINESupplier
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Shanghai Sunway Pharmaceutical Technology Co., Ltd
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- mzeng@3wpharm.com
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11-(PIPERAZIN-1-YL)DIBENZO[B,F][1,4]THIAZEPINE(5747-48-8)Related Product Information
- Quetiapine
- Metiapine
- ETHANOL, 2-[2-[4-(5-OXIDODIBENZO[B,F][1,4]THIAZEPIN-11-YL)-1-PIPERAZINYL]ETHOXY]- ,DIHYDROCHLORIDE
- 11-(1-PIPERAZINYL)-DIBENZO[B,F][1,4]THIAZEPIN HYDROCHLORIDE
- N-DES[2-(2-HYDROXYETHOXY)ETHYL] QUETIAPINE-D8
- 11-(PIPERAZIN-1-YL)DIBENZO[B,F][1,4]THIAZEPINE
- 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride
- QUETIAPINE SULFOXIDE
- 11-(1-Piperazinyl-d8)-dibenzo[b,f][1,4]thiazepin-7-ol
- 11-[4-(2-CHLORO-ETHYL)-PIPERAZIN-1-YL]-DIBENZO[B,F][1,4]THIAZEPINE
- 7-Hydroxy Quetiapine-D8
- 7-HYDROXY QUETIAPINE
- CLOTHIAPINE
- Quetiapine fumarate
- 11-(1-PIPERAZINYL)-DIBENZO[B,F][1,4]THIAZEPIN-7-OL