Rofleponide
Rofleponide Basic information
- Product Name:
- Rofleponide
- Synonyms:
-
- Rofleponide
- Rofleponide [inn]
- Unii-R9iq7gvl3e
- Pregn-4-ene-3,20-dione, 16,17-[(1R)-butylidenebis(oxy)]-6,9-difluoro-11,21-dihydroxy-, (6α,11β,16α)-
- CAS:
- 144459-70-1
- MF:
- C25H34F2O6
- MW:
- 468.534
- Mol File:
- 144459-70-1.mol
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Rofleponide Chemical Properties
- Boiling point:
- 597.0±50.0 °C(Predicted)
- Density
- 1.32±0.1 g/cm3(Predicted)
- pka
- 12.87±0.70(Predicted)
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Rofleponide Usage And Synthesis
Uses
Rofleponide is a synthetic glucocorticoid that has a high affinity for rat thymic glucocorticoid receptors and has high anti-inflammatory efficacy in experimental animal models[1].
References
[1] Thalén A, et al. Synthesis and structure elucidation of potential 6-oxygenated metabolites of (22R)-6α, 9α-difluoro-11β, 21-dihydroxy-16α, 17α-propylmethylenedioxypregn-4-ene-3, 20-dione, and related glucocorticosteroids[J]. Steroids, 2000, 65(1): 16-23. DOI:10.1016/s0039-128x(99)00080-x
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