REV 6207
REV 6207 Basic information
- Product Name:
- REV 6207
- Synonyms:
-
- REV 6207
- 2-[[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-pyrrolidin-1-ylamino]acetic acid
- Glycine, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-N-1-pyrrolidinyl- (9CI)
- CAS:
- 98056-23-6
- MF:
- C21H31N3O5
- MW:
- 405.49
- Mol File:
- 98056-23-6.mol
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REV 6207 Chemical Properties
- Boiling point:
- 577.5±60.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- pka
- 5.44±0.39(Predicted)
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REV 6207 Usage And Synthesis
Description
Rev 6207 is a non-sulfhydryl containing ACE-inhibitor.
Uses
Rev 6207 (free base) is a potent non-thiol angiotensin I converting enzyme inhibitor. Rev 6207 (free base) has comparable antihypertensive activity to Enalapril (HY-B0331) in awake monkeys with high renin activity and can be used in the study of hypertensive diseases[1].
References
[1] Hubbard J W, et al. Comparative hypotensive activity of REV 6207 and enalapril in the conscious furosemide‐treated monkey[J]. Drug Development Research, 1989, 17(1): 17-21.