TEI 6472
TEI 6472 Basic information
- Product Name:
- TEI 6472
- Synonyms:
-
- TEI 6472
- 2-[4-[(1R,2R)-2-[(E)-2-naphthalen-2-ylethenyl]cyclopropyl]butanoylamino]benzoic acid
- CAS:
- 151379-49-6
- MF:
- C32H39N3O5
- MW:
- 545.66916
- Mol File:
- 151379-49-6.mol
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TEI 6472 Usage And Synthesis
Description
Tei 6472 is a more hydrophilic form of TEI-1338, a new, selective lipoxygenase inhibitor.
Uses
TEI-6472, a naphthalene derivative, can suppress IgE responses both in vitro and in vivo. TEI-6472 causes significant inhibition of FceRI-mediated histamine release[1].
References
[1] H Ohmori, et al. Suppression of IgE antibody response in mice by a naphthalene derivative, TEI-6472. Int J Immunopharmacol. 1993 Jul;15(5):573-9. DOI:10.1016/0192-0561(93)90074-9