SCH 48973 Chemical Properties

Boiling point:

541.4±45.0 °C(Predicted)

Density 

1.329±0.06 g/cm3(Predicted)

storage temp. 

Store at -20°C

solubility 

DMSO:100.0(Max Conc. mg/mL);236.0(Max Conc. mM)

form 

Solid

color 

White to off-white

SCH 48973 Usage And Synthesis

Uses

Pocapavir (SCH-48973) is an orally active capsid inhibitor. Pocapavir prevents virion uncoating upon entry into the cell. Pocapavir has antiviral activity against polioviruses. Pocapavir also inhibits enterovirus infections[1].

References

[1] Collett MS, et al. Antiviral Activity of Pocapavir in a Randomized, Blinded, Placebo-Controlled Human Oral Poliovirus Vaccine Challenge Model. J Infect Dis. 2017 Feb 1;215(3):335-343. DOI:10.1093/infdis/jiw542