E 5090
E 5090 Basic information
- Product Name:
- E 5090
- Synonyms:
-
- E 5090
- (Z)-3-(4-Acetoxy-3-methoxy-5-ethyl-1-naphthalenyl)-2-methylpropenoic acid
- (Z)-3-(4-Acetoxy-5-ethyl-3-methoxy-1-naphthalenyl)-2-methylpropenoic acid
- E-5090【pharmaceutical】
- CAS:
- 131420-91-2
- MW:
- 0
- Mol File:
- 131420-91-2.mol
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E 5090 Usage And Synthesis
Description
E5090, a novel orally active inhibitor of IL-1 generation, has antiinflammatory properties.
Uses
E5090 is an orally active inhibitor of IL-1 generation which is converted in vivo into the pharmacologically active deacetylated form (DA-E5090). E5090 can be utilized in immunology research[1].
IC 50
IL-1
References
[1] Goto M, et al. A novel inhibitor of IL-1 generation, E5090: in vitro inhibitory effects on the generation of IL-1 by human monocytes. Agents Actions Suppl. 1991;32:225-9. DOI:10.1007/978-3-0348-7405-2_30