A 71497
A 71497 Basic information
- Product Name:
- A 71497
- Synonyms:
-
- A 71497
- 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carbaldehyde
- CAS:
- 134762-03-1
- MF:
- C19H16ClF3N4O2
- MW:
- 424.81
- Mol File:
- 134762-03-1.mol
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A 71497 Usage And Synthesis
Description
A 71497 is the 3-formyl derivative of the antibiotic tosufloxacin. It produces high plasma levels of tosufloxacin to improve solubility of the drug for the environment of the human body.
Uses
A-71497 is the 3-formyl derivative of the antibiotic Tosufloxacin (HY-B1802). A-71497 can produce high plasma levels of tosufloxacin upon both oral and subcutaneous administration to mice[1].
References
[1] Chu DT, et al. Synthesis and biological properties of A-71497: a prodrug of tosufloxacin. Drugs Exp Clin Res. 1990;16(9):435-443. PMID:2100244