Lilly 18947
Lilly 18947 Basic information
- Product Name:
- Lilly 18947
- Synonyms:
-
- Lilly 18947
- LY 18947 (for hydrobromide)
- Ethanamine, 2-[(3,5-dichloro[1,1'-biphenyl]-2-yl)oxy]-N,N-diethyl-
- CAS:
- 2600-77-3
- MF:
- C18H21Cl2NO
- MW:
- 338.27
- Mol File:
- 2600-77-3.mol
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Lilly 18947 Chemical Properties
- Boiling point:
- 150-162 °C(Press: 1 Torr)
- Density
- 1.156±0.06 g/cm3(Predicted)
- pka
- 9.44±0.25(Predicted)
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Lilly 18947 Usage And Synthesis
Description
Lilly 18947 is an inhibitor of cytochrome P450.
Uses
Lilly 18947 (free base) is a selective drug-potentiating agent that synergizes carbamate insecticides. Lilly 18947 (free base) inhibits a variety of detoxication mechanisms in mammals[1].
References
[1] FAHMY MA, et al. SELECTIVE SYNERGISM OF CARBAMATE INSECTICIDES ON HOUSE FLIES BY ARYLOXYALKYLAMINES. J Econ Entomol. 1965 Jun;58:451-5. DOI:10.1093/jee/58.3.451