aspergillic acid Chemical Properties

Melting point:

97-99° (methanol)

alpha 

D18 +13.3° (c = 3.9 in ethanol)

Boiling point:

365.71°C (rough estimate)

Density 

1.0594 (rough estimate)

refractive index 

1.4760 (estimate)

pka

5.5(at 25℃)

LogP

1.810 (est)

EPA Substance Registry System

Pyrazinol, 6-(1-methylpropyl)-3-(2-methylpropyl)-, 1-oxide, (+)- (490-02-8)

Safety Information

Toxicity

LDLo orl-mus: 200 mg/kg JOBAAY 45,433,43

aspergillic acid Usage And Synthesis

Chemical Properties

Yellow crystals. Insoluble in cold water; soluble in common organic solvents and dilute acids. Hydrochloride melts at 178C and is soluble in water.

Uses

Antibiotic.

Definition

ChEBI: Aspergillic acid is a member of pyrazines.

Safety Profile

Poison by ingestion andintraperitoneal routes. When heated to decomposition itemits toxic fumes of NOx.

Purification Methods

It is recrystallised from MeOH and is sublimed at 80o/10-3mm. [Dutcher J Biol Chem 171 321 1947, Beilstein 24 III/IV 235.]

aspergillic acid(490-02-8)Related Product Information

• 3-ISOBUTYL-1H-PYRAZIN-2-ONE
• aspergillic acid