4-HYDROXY-3-METHOXY-5-NITROBENZOIC ACID Chemical Properties

Melting point:

216℃

Boiling point:

386℃

Density 

1.564

Flash point:

187℃

storage temp. 

Sealed in dry,Room Temperature

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

3.82±0.10(Predicted)

color 

Pale Yellow to Yellow

4-HYDROXY-3-METHOXY-5-NITROBENZOIC ACID Usage And Synthesis

Uses

4-Hydroxy-3-methoxy-5-nitrobenzoic acid is used as an intermediate for Opicapone. Opicapone is a catechol-O-methyltransferase (COMT) inhibitor used to increase the availability and duration of action of L-Dopa, the standard of care for Parkinson's disease.