AMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE
AMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE Basic information
- Product Name:
- AMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE
- Synonyms:
-
- (4S)-4-Amino-4-carboxybutanehydroxamic acid
- (S)-4-Amino-4-carboxybutanehydroximic acid
- 3-[2-Oxo-2-(hydroxyamino)ethyl]alanine
- L-Glutamic acid γ-hydroxamate
- N5-Hydroxy-L-glutamine
- (2S)-5-amino-2-(hydroxyamino)-5-keto-valeric acid
- (2S)-5-amino-2-(hydroxyamino)-5-oxopentanoic acid
- (2S)-5-azanyl-2-(hydroxyamino)-5-oxo-pentanoic acid
- CAS:
- 1955-67-5
- MF:
- C5H10N2O4
- MW:
- 162.14
- Mol File:
- 1955-67-5.mol
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AMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE Chemical Properties
- Melting point:
- 154 °C
- Density
- 1.432±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- pka
- 2.21±0.10(Predicted)
- form
- powder
- color
- white to off-white
MSDS
- Language:English Provider:SigmaAldrich
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AMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATE Usage And Synthesis
Uses
L-Glutamic acid γ-monohydroxamate has been used as a standard to calculate transglutaminase (TGase) activity.
Definition
ChEBI: A hydroxamic acid that is L-glutamine hydroxylated at N-5.
Biochem/physiol Actions
L-Glutamic acid γ-monohydroxamate [L-Glu(gamma)HXM] is used as a vanadium ligand which potentiates vanadiums metabolic activity. L-Glu(gamma)HXM is also used as a substrate for E. coli asparagine synthetase B and as an ATP-dependent irreversible inhibitor of Escherichia coli gamma-glutamylcysteine synthetase.
AMINO ACID HYDROXAMATES L-GLUTAMIC ACID GAMMA-MONOHYDROXAMATESupplier
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Sigma-Aldrich
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