Pyridine,4-chloro-2,6-dimethoxy- Chemical Properties

Melting point:

64-65℃

Boiling point:

211℃

Density 

1.217

Flash point:

81℃

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

Pyridine,4-chloro-2,6-dimethoxy- Usage And Synthesis

Synthesis

Step F: 2,4,6-trichloropyridine (3.0 g, 19 mmol) was suspended in anhydrous toluene (35 ml) and solid sodium methanol (3.6 g, 76 mmol) was added. The reaction mixture was heated and stirred under reflux conditions for 3 hours. After completion of the reaction, the mixture was filtered and the filtrate was concentrated under reduced pressure to remove the solvent to afford 2.5 g of the colorless oily product 4-chloro-2,6-dimethoxypyridine (76% yield). Mass spectrometric analysis (APCI) showed m/z = 173.9 [M + H]+.

References

[1] Patent: WO2012/41872, 2012, A1. Location in patent: Page/Page column 95

Pyridine,4-chloro-2,6-dimethoxy-(62616-14-2)Related Product Information

• 2,6-DIHYDROXYPYRIDINE HYDROCHLORIDE
• Pyridine,4-chloro-2,6-dimethoxy-
• 4-CHLORO-2-METHOXY-PYRIDINE
• 4-Chloro-2-hydroxypyridine