(S) QuinoxP(R) Chemical Properties

Melting point:

100-105 °C

alpha 

+54.3° (c 1.0, CHCl3)

Boiling point:

447.6±45.0 °C(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

Powder

pka

-0.54±0.59(Predicted)

color 

orange

optical activity

[α]22/D +55°, c = 1 in chloroform

Safety Information

Hazard Codes 

Xn

Risk Statements 

22-36/37/38

Safety Statements 

26

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

HS Code 

2933.99.8290

(S) QuinoxP(R) Usage And Synthesis

Reaction

1. Ligand for the rhodium-catalyzed, asymmetric hydrogenation of dehydroamino acid esters and α-enamides.
2. Ligand for the rhodium-catalyzed, asymmetric 1,4-addition of arylboronic acids to α,β-unsaturated carbonyl compounds.
3. Ligand for the rhodium-catalyzed, asymmetric alkylative ring opening reaction
4. Ligand for the palladium-catalyzed asymmetric allylic alkylation and amination of racemic substrates.
5. Ligand for the ruthenium-catalyzed asymmetric hydrogenation of ketones.
6. Ligand for the rhodium-catalyzed, asymmetric hydroacylation of 1,1-disubstituted alkenes with aldehydes.
7. Ligand for the silver-catalyzed asymmetric nitroso aldol reaction.