2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE Chemical Properties

storage temp. 

Desiccate at +4°C

solubility 

Soluble to 15 mM in ethanol with gentle warming and to 80 mM in DMSO

form 

Powder

2-(2-PYRIDINYL)-(3H)-INDOL-3-ONE-1-OXIDE 4-METHYLBENZENESULFONATE Usage And Synthesis

Uses

PIT is a purinergic P2Y receptor ligand.

Biological Activity

Purinergic P2Y receptor ligand. Displays irreversible antagonism at P2Y receptors in some smooth muscles but potentiates responses to ATP in other systems (chick brain recombinant P2Y 1 receptor and sympathetic/purinergic nerve stimulation).

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