DIMETHYL TRIMETHYLSILYL PHOSPHITE Chemical Properties

Boiling point:

36-37 °C/11 mmHg (lit.)

Density 

0.954 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.410(lit.)

Flash point:

102 °F

storage temp. 

2-8°C

Specific Gravity

0.954

Hydrolytic Sensitivity

7: reacts slowly with moisture/water

BRN 

1849308

Safety Information

Hazard Codes 

C

Risk Statements 

10-34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 2920 8/PG 2

WGK Germany 

3

F 

10-13

TSCA 

No

HazardClass 

3.2

PackingGroup 

III

MSDS

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DIMETHYL TRIMETHYLSILYL PHOSPHITE Usage And Synthesis

Chemical Properties

clear colorless liquid

Uses

Dimethyl trimethylsilyl phosphite may be used in the preparation of:

• protected phosphoamino acid, Fmoc-Abu(PO₃Me₂)-OH, used in Fmoc/solid-phase peptide synthesis
• phosphoenolpyruvate (PEP) via trimethylsilylation, bromination and Perkow reaction
• sialyl phosphonate
• sulfonamide phosphonates