Candoxatrilat
Candoxatrilat Basic information
- Product Name:
- Candoxatrilat
- Synonyms:
-
- 4α-[[[1-[(S)-2-Carboxy-3-(2-methoxyethoxy)propyl]cyclopentyl]carbonyl]amino]cyclohexane-1α-carboxylic acid
- UK-73967
- Candoxatrilat [usan:inn:ban]
- Cyclohexanecarboxylic acid, 4-(((1-((2S)-2-carboxy-3-(2-methoxyethoxy)propyl)cyclopentyl)carbonyl)amino)-, cis-
- U 73967
- Unii-7wu8Bz90th
- Candoxatrilat (UK 73967)
- (1s,4s)-4-{1-[(2S)-2-carboxy-2-[(2-methoxyethoxy)methyl]ethyl]cyclopentaneamido}cyclohexane-1-carboxylic acid
- CAS:
- 123122-54-3
- MF:
- C20H33NO7
- MW:
- 399.481
- Mol File:
- 123122-54-3.mol
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Candoxatrilat Chemical Properties
- Melting point:
- 108.5-109.1°
- alpha
- D +1.4° (c = 1 in methanol)
- Boiling point:
- 642.1±55.0 °C(Predicted)
- Density
- 1.22±0.1 g/cm3(Predicted)
- pka
- 4.32±0.11(Predicted)
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Candoxatrilat Usage And Synthesis
Uses
Antihypertensive.
Definition
ChEBI: Candoxatrilat is a dicarboxylic acid monoamide obtained by formal condensation between the amino group of cis-4-aminocyclohexanecarboxylic acid and the cyclopentanecarboxylic acid group of 1-[(2S)-2-carboxy-3-(2-methoxyethoxy)propyl]cyclopentanecarboxylic acid. A potent inhibitor of neutral endopeptidase (NEP, neprilysin, EC 3.4.24.11), it is used as its 2,3-dihydro-1H-inden-5-yl ester prodrug in the treatment of chronic heart failure. It has a role as an EC 3.4.24.* (metalloendopeptidase) inhibitor. It is a dicarboxylic acid and a dicarboxylic acid monoamide.
CandoxatrilatSupplier
HANGZHOU CLAP TECHNOLOGY CO.,LTD
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- 86-571-88216897,88216896 13588875226
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Changzhou Bojia Biomedical Technology Co., Ltd.
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- 2122619822
- czbjpharma@126.com
Nanjing Shizhou Biology Technology Co.,Ltd
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- 025-85560043 15850508050
- cindy.huang@synzest.com
TargetMol Chemicals Inc.
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- +1-781-999-5354
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