Basic information Safety Supplier Related

CODEINE HYDROCHLORIDE

Basic information Safety Supplier Related

CODEINE HYDROCHLORIDE Basic information

Product Name:
CODEINE HYDROCHLORIDE
Synonyms:
  • Codeinum Hcl
  • NUXLENPAZQNFAM-FFHNEAJVSA-N
  • CODEINE HYDROCHLORIDE DIHYDRATE
  • (4R,4aR,7S,7aR,12bS)-9-Methoxy-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol hydrochloride
CAS:
1422-07-7
MF:
C18H22ClNO3
MW:
335.83
EINECS:
215-829-5
Mol File:
1422-07-7.mol
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CODEINE HYDROCHLORIDE Chemical Properties

Melting point:
~280° with some decompn
alpha 
D22 -108°
storage temp. 
2-8°C
solubility 
Soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in cyclohexane.
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Safety Information

Toxicity
LD50 s.c. in mice: 300 mg/kg (Eddy, Sumwalt)
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CODEINE HYDROCHLORIDE Usage And Synthesis

Chemical Properties

White or almost white, crystalline powder or small, colourless crystals.

Uses

Opioid receptor agonist; analgesic.

Contact allergens

Codeine has been reported as an occupational sensitizer in workers in the production of opium alkaloids. Codeine has been responsible for fixed drug eruptions or generalized dermatitis. Cross-sensitivity is expected to morphine.

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