CALPAIN INHIBITOR XI Chemical Properties

Density 

1.145±0.06 g/cm3(Predicted)

storage temp. 

2-8°C

solubility 

DMSO: 5mg/mL

pka

11.10±0.46(Predicted)

form 

Solid

color 

white to off-white

Sensitive 

Light Sensitive

CALPAIN INHIBITOR XI Usage And Synthesis

Uses

A cell-permeable dipeptidyl -ketoamide that acts as a potent, highly selective, reversible, and active site inhibitor of calpain-1 and -2

Biological Activity

Cell permeable: yes', 'Primary Target
calpain 1, calpain 2', 'Product does not compete with ATP.', 'Reversible: yes', 'Target Ki: 140 nM and 41 nM, against calpain-1 and -2, respectively