7S,8R,17R-TRIHYDROXY-4Z,9E,11E,13Z,15E19Z-DOCOSAHEXAENOIC ACID Chemical Properties

Boiling point:

609.2±55.0 °C(Predicted)

Density 

1.101±0.06 g/cm3(Predicted)

storage temp. 

Store at -80°C

solubility 

DMF: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.05 mg/ml

pka

4.58±0.10(Predicted)

7S,8R,17R-TRIHYDROXY-4Z,9E,11E,13Z,15E19Z-DOCOSAHEXAENOIC ACID Usage And Synthesis

Uses

17(R)-Resolvin D1 is an exhibitor of a dose-dependent reduction in leukocyte infiltration.is used in methods for predicting patient response to disease-modifying antirheumatic drug (DMARD).

Definition

ChEBI: Aspirin-triggered resolvin D1 is a member of the class of resolvins that consists of docosa-4Z,9E,11E,13Z,15E,19Z-hexaenoic acid carrying three hydroxy substituents at positions 7, 8, and 17 (the 7S,8R,17S-stereoisomer). It has a role as an anti-inflammatory agent, an antiviral agent, an analgesic, a TGFbeta receptor antagonist, a nephroprotective agent, an anti-allergic agent and a human xenobiotic metabolite. It is a resolvin, a secondary allylic alcohol and a hydroxy polyunsaturated fatty acid.