Basic information Safety Supplier Related

(2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone

Basic information Safety Supplier Related

(2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone Basic information

Product Name:
(2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone
Synonyms:
  • (2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone
  • 2-Butyl-3-(4-hydroxybenzoyl)-5-nitrobenzofuran
  • 2-N-Butyl-3-(4-hydroxybenzoyl)-5-nitrobenzofuran
  • 2-butyl-3-[(4-Methoxyphenyl)carbonyl]-6-nitro-1-benzofuran
  • 22-(n-Butyl)-3-(4-hydroxybenzoyl)-5-nitrobenzofuran
  • (2-Butyl-5-nitro-1-benzofuran-3-yl)(4-hydroxyphenyl)Methanone
  • (2-butyl-5-nitro-3-benzofuran-3-yl)(4- hydroxyphenyl) Methanone
  • 1-(2- Butyl-5-nitro-1-benzofuran-3-yl)-1-(4 hydroxyphenyl)methanone
CAS:
141645-16-1
MF:
C19H17NO5
MW:
339.34
EINECS:
464-300-7;604-244-4
Product Categories:
  • API
  • Dronedarone intermediate
Mol File:
141645-16-1.mol
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(2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone Chemical Properties

Melting point:
129 - 131°C
Boiling point:
559.5±50.0 °C(Predicted)
Density 
1.302±0.06 g/cm3(Predicted)
vapor pressure 
0Pa at 25℃
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
7.40±0.15(Predicted)
form 
Solid
color 
White to Off-White
Water Solubility 
220μg/L at 20℃
InChI
InChI=1S/C19H17NO5/c1-2-3-4-17-18(19(22)12-5-8-14(21)9-6-12)15-11-13(20(23)24)7-10-16(15)25-17/h5-11,21H,2-4H2,1H3
InChIKey
ZJZKLBXEGZKOBW-UHFFFAOYSA-N
SMILES
C(C1C2=CC([N+]([O-])=O)=CC=C2OC=1CCCC)(C1=CC=C(O)C=C1)=O
LogP
3.72 at 24℃
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Safety Information

HS Code 
2932996560
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(2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone Usage And Synthesis

Uses

(2-Butyl-5-nitro-3-benzofuranyl)(4-hydroxyphenyl)methanone (Dronedarone USP Related Compound D) is a related compound of Dronedarone (D679445), a drug used for the treatment of atrial fibrillation and atrial flutter in patients who have suffered cardiac arrhythmias.

Flammability and Explosibility

Non flammable

(2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanoneSupplier

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