5-Acetyl-2-chloropyrazine Chemical Properties

Melting point:

43-46°C (dec.)

Boiling point:

259.5±35.0 °C(Predicted)

Density 

1.311±0.06 g/cm3(Predicted)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

-3.33±0.10(Predicted)

form 

Solid

color 

Dark Yellow

InChI

InChI=1S/C6H5ClN2O/c1-4(10)5-2-9-6(7)3-8-5/h2-3H,1H3

InChIKey

NMMJHUZSTPHGCA-UHFFFAOYSA-N

SMILES

C(=O)(C1=NC=C(Cl)N=C1)C

Safety Information

HS Code 

2933998090

5-Acetyl-2-chloropyrazine Usage And Synthesis

Chemical Properties

Yellow Solid

Uses

5-Acetyl-2-chloropyrazine is used in the preparation of 5,7-disubstituted-4-aminopyrido[2,3-d]pyrimidines as adenosine kinase inhibitors.

Chemical Reactivity

5-Acetyl-2-chloropyrazine serves as a versatile building block in organic synthesis, exhibiting notable reactivity due to its electrophilic nature. The presence of the acetyl and chloropyrazine moieties facilitates nucleophilic attack, leading to diverse substitution reactions.