N-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoroMethyl)phenyl)propanaMide Chemical Properties

Melting point:

90-92℃ (cyclohexane )

Boiling point:

530.5±50.0 °C(Predicted)

Density 

1.210±0.06 g/cm3(Predicted)

storage temp. 

Sealed in dry,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

pka

15.18±0.46(Predicted)

color 

Off-White to Light Brown

Stability:

Hygroscopic

N-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoroMethyl)phenyl)propanaMide Usage And Synthesis

Uses

N-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoroMethyl)phenyl)propanaMide is a pharmaceutical intermediate ingredient used in the preparation of cinacalcet and its salts. Cinacalcet is used for the management and treatment of secondary hyperparathyroidism (in the dialysis population), primary hyperparathyroidism (where the patient may not be a candidate for surgical treatment), and for the treatment of end-stage renal disease or the prevention of calcification in dialysis patients.

N-((R)-1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoroMethyl)phenyl)propanaMide(1005450-55-4)Related Product Information

• (αR)-α-Methyl-N-[3-[3-(trifluoroMethyl)phenyl)propyl]-1-napthaleneMethanaMine-N-oxide
• (R)-1-(5,6-dihydronaphthalen-1-yl)ethan-1-amine
• 3-(3-Trifluoromethylphenyl)propionic acid
• Cinacalcet hydrochloride
• 1'-Acetonaphthone
• Methanesulfonic acid 3-(3-trifluoroMethylphenyl)propyl ester
• 3-(3-METHYLPHENYL)PROPIONIC ACID
• N-(1-(5,6,7,8-tetrahydronaphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide
• 3-[o-(alpha,alpha,alpha-trifluorotolyl)]propionic acid
• 1-NaphthaleneMethanaMine, 5,6,7,8-tetrahydro-α-Methyl-, (αR)-
• 1-NaphthaleneMethanaMine, α-Methyl-N-[[3-(trifluoroMethyl)phenyl]Methyl]-, (αR)-
• (R)-1-(Naphthalen-2-yl)ethanamine hydrochloride
• (R)-N-(1-(naphthalen-1-yl)ethyl)-3-(M-tolyl)propan-1-aMine
• Cinacalcet 7,8-Dihydro Racemate HCl
• Cinacalcet Impurity B
• 4-(TRIFLUOROMETHYL)HYDROCINNAMIC ACID
• Cinacalcet Impurity D
• 3-(3'-TRIFLUOROMETHYL PHENYL) PROPANOL