Isoquinoline, 1,7-dichloro-4-Methoxy- Chemical Properties

Melting point:

137.0 to 142.0 °C

Boiling point:

355.7±37.0 °C(Predicted)

Density 

1.384±0.06 g/cm3(Predicted)

storage temp. 

under inert gas (nitrogen or Argon) at 2-8°C

form 

powder to crystal

pka

0.98±0.34(Predicted)

color 

White to Yellow to Orange

Safety Information

HS Code 

2933.49.7000

Isoquinoline, 1,7-dichloro-4-Methoxy- Usage And Synthesis

Uses

1,7-Dichloro-4-methoxyisoquinoline acts as a reagent in the synthesis and biological evaluations of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease. Preparation, SAR of methoxyisoquinoline derivatives and discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection.

Isoquinoline, 1,7-dichloro-4-Methoxy-(630423-36-8)Related Product Information

• Asunaprevir
• CyclopropanecarboxaMide, 1-aMino-N-(cyclopropylsulfonyl)-2-ethenyl-,(1R,2S)-, 4-Methylbenzenesulfonate(1:1)
• t-Butyl(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-vinylcyclopropylcarbamate