(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol Mesylate Chemical Properties

Melting point:

173.5-174.5℃

storage temp. 

Inert atmosphere,Room Temperature

solubility 

DMSO (Sparingly), Methanol (Slightly)

form 

Solid

color 

Off White to Pale Beige

Stability:

Hygroscopic

(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol Mesylate Usage And Synthesis

Uses

(2R,3R)- 2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol Methanesulfonate is a useful synthetic intermediate in the synthesis of Efinaconazole; a topical antifungal for onychomycosis. (2R,3R)- 2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol Methanesulfonate is also used as a reagent in the synthesis of Ravuconazole; an ergosterol biosynthesis inhibitor and antifungal.

Uses

(2R,3R)- 2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol Methanesulfonate is a useful synthetic intermediate in the synthesis of Efinaconazole (E435070); a topical antifungal for onychomycosis. (2R,3R)- 2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol Methanesulfonate is also used as a reagent in the synthesis of Ravuconazole (R128000); an ergosterol biosynthesis inhibitor and antifungal.

(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol Mesylate(1175536-50-1)Related Product Information

• Efinaconazole Impurity 22
• Efinaconazole Impurity 21
• 2,3-Butanediol, 2-(2,5-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-, (2R,3R)- (2R,3R)-2-(2,5-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2,3-butanediol
• (2R,3R)-3-((1H-1,2,4-Triazol-1-yl)methyl)-6-fluoro-3-hydroxy-2-methyl-4''-methylenespiro[indoline-1,1''-piperidin]-1-ium fluoride
• (2S,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol