1,2,3,4,5,6-HEXAHYDRO-6-METHYL-AZEPINO[4,5-B]INDOLE HYDROCHLORIDE Chemical Properties

Boiling point:

383.0±32.0 °C(Predicted)

Density 

1.17±0.1 g/cm3(Predicted)

storage temp. 

Desiccate at +4°C

pka

10.73±0.20(Predicted)

1,2,3,4,5,6-HEXAHYDRO-6-METHYL-AZEPINO[4,5-B]INDOLE HYDROCHLORIDE Usage And Synthesis

Uses

PNU 22394 is a potent SR-2C agonist and partial SR-2A/SR-2B agonist. Central nervous system sedative. A tryptamine derivative which has hyperthermic effects.

Biological Activity

Potent 5-HT 2C agonist and partial 5-HT 2A /5-HT 2B agonist. Non-selective between 5-HT 2 receptor subtypes (K i values are 18, 18 and 66 nM for human recombinant 5-HT 2C , 5-HT 2A and 5-HT 2B receptors respectively). Reduces food intake in rats following subcutaneous administration and displays anorexigenic effects in humans.

1,2,3,4,5,6-HEXAHYDRO-6-METHYL-AZEPINO[4,5-B]INDOLE HYDROCHLORIDE(15923-78-1)Related Product Information

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