Cefiderocol Chemical Properties

storage temp. 

Store at -20°C, stored under nitrogen,unstable in solution, ready to use.

solubility 

DMSO:50.0(Max Conc. mg/mL);66.47(Max Conc. mM)

form 

Solid

color 

White to off-white

Cefiderocol Usage And Synthesis

Uses

Cefiderocol, is a novel parenteral siderophore cephalosporin conjugated with a catechol moiety, that has a characteristic antibacterial spectrum with a potent activity against a broad range of aerobic Gram-negative bacterial species,

reaction suitability

reagent type: chelator

Biological Activity

Mode of Action: Cefiderocol binds to specific proteins called penicillin-binding proteins (PBPs) located on the bacterial cell wall. This binding affinity inhibits the synthesis of the bacterial cell wall, leading to cell lysis and bacterial death.

Antimicrobial Spectrum: Cefiderocol has strong antimicrobial properties, especially against a wide spectrum of Gram-negative pathogens. Due to its siderophore core it is also a natural iron-chelator, which adds to its antibacterial activities.

Cefiderocol(1225208-94-5)Related Product Information

• BACILLUSLICHENIFORMIS